Hyaluronidase is a depolymerized enzyme that catalyzes the degredation of hyaluronic acid. It is a treatment to accelerate the natural breakdown of hyaluronic acid. It increases tissue permeablity and promotes the spread or dispersion of other injected fillers.Hyaluronidase is only used to decrease the lumps/bumps created while using injectable dermal fillers with hyaluronic acid. Furthermore, hyaluronidase facilitates removal of intraderm water bags and promotes the penetration of other active substances through the skin.